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Leukemia genetic risk factors

Researchers have discovered more information about what makes some people for leukemia. Scientists now know of 10 genetic variants associated with chronic lymphocytic leukemia (CLL), scientists at the European Institute Cancer Research who led the study. The four new genes are common in people (CLL).

This finding is very important because (CLL) is one of the four main types of leukemia. Of 15 490 new cases of CLL are diagnosed in 2009. From about 85,710 people in the United States live with or are in remission of chronic lymphocytic leukemia. In recent years, new therapies have been approved and other new treatments potential are studied in clinical trials. Progress toward recovery is underway, however, a remedy has not been reached.

Richard Houlston, who led the study, said it has confirmed the genetic risk of CLL and showed that it was caused by a single gene, because the cumulative effect of many genetic changes. Those who get the disease may have some or all of the genes. The Most of the genes of an individual is the highest probability of developing the disease.

At this stage, doctors could not say what caused the cell changes leading to CLL. Not at all prevent chronic lymphocytic leukemia, and it was contagious. Houlston says now believe that "The People who have more than 13 risk factors are seven times more likely than the general population to develop CLL.

According to Reuters, the risk factors been identified by a technical analysis geneticists have used before to find risk genes in breast, prostate, testis, brain and colon cancer and childhood leukemia. The researchers scanned the genes of patients with CLL in 2503 and 5789 compared to healthy people, the search differences in DNA between the two groups.

The researchers said that people with CLL have at least one genetic risk. David Grant, Director Scientific leukemia research charity which funded the study, said that confirmed suspicions long ago that this form of Leukemia may be hereditary.

The researchers say they have more to investigate the families to discover which genes are the most important.

About the Author

Lenneice A. Drew is an experienced journalist currently focused on healthcare reform . She is working to help others achieve better lives by finding affordable health insurance alternatives and reporting stories related to the healthcare industry. She lives in Miami, Florida.



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