prostate screening guidelines
prostate screening guidelines
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Cancer: FAQ
Manjari Peiris
A person eight deaths worldwide is caused by cancer. The cancer causes more deaths worldwide than AIDS, tuberculosis and malaria combined. This is second leading cause of death in developed countries (after heart disease) and the third leading cause of death in developing countries (hereinafter heart disease and diarrhea).
Cancer is a group of diseases characterized by uncontrolled proliferation of cells abnormal. If the epidemic is not controlled, it can cause death. Cancer is caused by external factors (tobacco, snuff, products chemical, radiation and infectious organisms) and internal factors (inherited mutations, hormones, immune conditions and mutations that occur in metabolism). These causal factors may act together or in sequence to initiate or promote carcinogenesis. The development of most cancers requires several steps which extend over several years. Some cancers are prevented by eliminating exposure to tobacco and snuff and other factors that accelerate this process. Other malignant potential can be detected before cells become cancer or at an early stage when the disease is most treatable. Cancer is treated by surgery, radiotherapy, chemotherapy, hormones, and immunotherapy.
The burden of cancer is increasing in developing countries as infant mortality and the decline in deaths from infectious diseases and more people live to advanced age. As people in developing countries to adopt an increased consumption of foods rich fat and calorie levels and reduced physical activity, full of common cancers in Western countries has increased, if preventive measures are not widely applied.
It is estimated that by 2050 the global burden is expected to grow 27 million new cancer cases and 17.5 million of cancer death, simply because of the growing and aging population.
The three most common cancers diagnosed in economically developed countries are prostate, lung and bronchus, colon in men and breast, colorectal and lung and bronchus, and among women. The three most common cancers diagnosed in developing countries are lung and bronchus, stomach and liver in humans and breast, cervix and stomach in women. In the economically developed and developing three most common cancers are also the three leading causes of cancer deaths.
Several major cancers associated with chronic infectious diseases (including stomach and cervical cancer) are less frequent than are the economically developed countries, while cancers associated with smoking and model Western diet, physical inactivity, and reproduction (especially lung and bronchus, breast and colorectal) increase with economic development.
Factors contributing to regional differences in types of cancer burden include regional variations in the prevalence of factors risk, the availability and use of medical practices, such as cancer screening, the availability and quality of treatment integrity information and age structure. Currently, two of the three leading cancers in men (stomach and liver) and women (cervix and stomach) in developing countries are related to infection. Stomach cancer remains the world's most common infection related to cancer, followed closely by the liver and cervix. About 15% of all cancer cases worldwide are attributable to infections. This percentage is almost three times higher in developing countries than in developed countries.
The incidence of cancer often diagnosed or death also varies by geographic area and countries and country parishes.
It is estimated that more than half of all new cancer cases and cancer deaths worldwide are potentially preventable. Cancers related to tobacco use, alcohol abuse and obesity more effectively through a combination of education and social policies that encourage healthy behaviors and discourage unhealthy practices. Certain cancers are related to infectious agents such as hepatitis B virus, human immunodeficiency virus (HIV), human papillomavirus and Helicobacter pylori. could be avoided through interventions existing, such as vaccines, antibiotics, improved sanitation, and education. Some types of cancers, including colorectal cancer and cervix can be prevented by detecting and removing pre-cancerous lesions through regular screenings by a professional Health.
Early detection of cancer is important because it provides a greater chance of successful treatment. Cancers that can be detected early through screening include breast, cervical, colorectal, oral cavity and skin worship. The screening has proven effective in reducing disease severity and mortality for all sites except prostate and skin. Detection early treatment for most of these cancers are not available in developing countries due to limited resources.
The risk cancer increases with age, although anyone can develop cancer. Cancer cases newly diagnosed in developed countries, 78% were under age 55. In developing countries was 58%. The difference is mainly due to changes in the age structure of population. People in developing countries are younger and have a lower proportion of elderly in whom the cancer more frequently.
Cancer researchers use the term "risk" in two forms, life risk or relative risk. Life risk refers to the probability that individual to develop or die of cancer over a lifetime.
The relative risk is a measure of the strength of association between a factor risk and a particular type of cancer. We compared the risk of developing cancer in people with a certain exposure or trait risk in people without this functionality. Male smokers are nearly 23 times more likely to develop lung cancer than non-smokers, so their relative risk is 23. Most relative risks are not as great. A woman with a history of breast cancer (mother, sister or daughter) is about twice the risk of developing cancer breast compared to women without family history.
Most genetic defects that affect cancer risk is not hereditary, but the result of damage to genes that occur throughout life. Damage to genes may be due to factors internal, such as hormones or metabolism of nutrients into cells, or external factors, such as snuff, chemicals, and sunlight. It is estimated that 5-10% of all cancers are strongly hereditary, which means that people who inherit a particular genetic alteration, have a risk high of developing cancer in particular. It is thought that many cancers result from a combination of hereditary and environmental factors.
The total number of cancer survivors in the world is unknown. Information on cancer registration and survival are not on file. However, the International Agency for Cancer Research estimates that in 2002 were approximately 24.6 million cancer survivors around the world who had been diagnosed during the last five years. Some of these people were free of cancer, while others still had evidence of cancer and may have treated. The number of people with a history of cancer within the next few years should increase with improved survival and growth provided and the aging population.
The survival of a specific type of cancer is usually measured by the proportion of people diagnosed with cancer are alive five years after diagnosis. Survival rates from cancer in a population affected by a number of factors, most Importantly, the type of cancer occurring, steps in which cancer is diagnosed and if treatment is available.
Large differences in survival between the developed and developing countries. This differentiation is mainly attributable to the increased availability of detection Early and effective in their respective countries. Also due in part to detect cancers earlier in the course of the disease by screening and detection of certain cancers that could step forward. Similar variations are observed throughout the world for cancer of the colon, uterus, cervical and prostate cancers, also for early detection and better treatment are responsible for improved survival. Regarding the children and other cancers, the availability of treatment is largely responsible for improved survival rates in developed countries.
Primary prevention is currently the most effective defense against the risk factors of cancer known.
To determine the extent or spread of disease at diagnosis warrant is required. A number of different classification systems are used to classify tumors
The financial cost of cancer is important. The costs are indirect (expenditure of resources and treatment, rehabilitation related to the disease, lost economic output due to lost work days, premature death etc. There are also hidden costs. With growth and aging of the population, prevention efforts are important to help reduce new cases of cancer, human suffering and economic costs.
The success of national policies to fight against cancer and awareness programs on cancer, reduce exposure risk factors, provide information and support for adopting healthy lifestyles, and increase the proportion of cancers detected early.
The World Health recommends that the four basic approaches in the economic development of a country should be considered when the development of national strategies to fight against cancer.
Primary prevention are those where exposure to carcinogenic factors such as smoking, diet, physical inactivity, occupational exposures and chronic infections must be eliminated. Primary Prevention is the greatest potential public health and the most profitable long-term fight against cancer. Approaches primary prevention include vaccination against infectious agents that cause certain types of cancer, effective tobacco control, reduction consumption of alcohol, maintaining healthy body weight and a lifestyle physical activity, dietary interventions, the sun and UV prevention, reducing occupational exposure to carcinogens and pharmacological interventions.
The main objective of screening early secondary prevention through screening is to detect precancerous changes or cancer early, when it can be treated more effectively. Early detection is useful only if it led to detailed monitoring of diagnosis and effective treatment. There are two strategies for screening, opportunistic screening sporadically requested by a doctor or individually or collectively review in which a given population is contacted and asked to be examined at regular intervals.
The first step to treating cancer is the Early diagnosis and careful clinical evaluation including pathology. Once the diagnosis is confirmed is necessary to determine the stage cancer, where the main objectives are to assist in the choice of treatment to determine the prognosis and standardize the design of treatment protocols investigation. The main methods of treating cancer are surgery, chemotherapy and radiotherapy. These treatments can be used only in combination.
Most cancer patients in advanced stages. The only realistic treatment option is, therefore, relief pain and palliative care. The World Health has developed guidelines for the treatment of cancer pain. He also developed guidelines for assessing national drug policies to ensure the availability of opiates for medical and scientists. WHO has played an important role in promoting effective management of pain and monitoring the availability of opiates in the world.
Data for this article from the American Cancer Society
About the Author
Manjari Peiris
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prostate screening failed to increase lifespan
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